Mumford announced his decision on Friday after extensive medical consultation. 

The 31-year-old has been battling ankle and knee problems for several years, but it has all become too much for the former Sydney Swan.

Mumford suffered a serious ankle injury during 2015, with his most recent injury forcing him out of the Giants' AFL Finals campaign. 

Mumford is a one-time Premiership winner with the Swans, and also won the Kevin Sheedy Medal for best and fairest at the Giants in 2014. 

He retires after 172 games in the AFL after making his debut for Geelong in 2008.

“While my mind was ready to go for another season, the medical advice told me something very different,” Mumford said. 

“I’ve loved my time playing for the Giants but I know this is the right decision when it comes to being able to play with my kids for years to come.

“I couldn’t have asked for more from the past decade in the AFL and I’d like to thank everyone who has helped me along this journey."

Mumford will continue with the Giants next season however as a part-time ruck coach.

“I’m excited about the next stage of my life and continuing to help the Giants in a role I’m really looking forward to," he added.