Salter has been a key part of Queensland's dominance in State of Origin and Australia's dominance in Test football over the past decade.

The legendary fullback has played in 29 Origin matches for Queensland and 30 Tests for Australia, while starring for the Melbourne Storm in the NRL.

"I just feel it's time," Slater said.

"I'm 35 this year. This will be my 15th year for Queensland. I had a fair indication that the World Cup last year would be the last time I played for Australia. It's been on my mind for a while. I always felt this would be my last Origin series."

Slater will play at fullback for the Maroons in State of Origin Game I next Wednesday.

"We say goodbye to Cam, Cooper and Johnathan who have been fantastic players for Queensland over a long period of time and have been at the centre of big moments in the last decade, but I am really excited about playing alongside some of the young guys coming through and being part of that plan to bring them along," he said.

"I am going out knowing that I can contribute to the team. It would have been disappointing being selected knowing that I was past it and only being selected on my reputation. I would like to finish my representative career knowing I can make a difference."