As it stands, only five men of the current top 10 will make their way to Brazil.

Representatives for Wawrinka said the 31-year-old was advised by his medical team to “reduce his physical activity for an undetermined period” after he “felt increasing pain” during the Rogers Cup in Toronto last week where he lost in the semi finals.

The No.4 seed joins No.3 Roger Federer, No. 7 Milos Raonic, No. 8 Tomas Berdych and No. 10 Dominic in withdrawing from Games.

No. 5 Rafael Nadal has been testing his fitness in Brazil after suffering a wrist injury at the French Open in a bid to compete, although it is unlikely the 30-year-old will take to the court.

Play begins on Saturday.